173550-33-9

173550-33-9 structure

Name: 3,5-bis-(4-Nitrophenoxy)benzoic acid
Chemical Name: 3,5-Bis(4-nitrophenoxy)benzoic Acid
CAS Number: 173550-33-9
Molecular Formula: C₁₉H₁₂N₂O₈
Molecular Weight: 396.30700
Catalog: Research Areas Metabolic Disease
Create Date: 2018-07-25 15:38:10
Modify Date: 2025-09-16 09:27:40
3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum[1].

Name	3,5-Bis(4-nitrophenoxy)benzoic Acid
Synonyms	MFCD02093450 3,5-BIS(4-NITROPHENOXY)BENZOIC ACID

Description	3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Wu SY, et al. Compound W, a 3,3'-diiodothyronine sulfate cross-reactive substance in serum from pregnant women--a potential marker for fetal thyroid function. Pediatr Res. 2007;61(3):307-312. [2]. Ran Y, et al. Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase Inhibitors. PLoS One. 2015;10(6):e0128619. Published 2015 Jun 5. [3]. Greife A, et al. Canonical Notch signalling is inactive in urothelial carcinoma. BMC Cancer. 2014;14:628. Published 2014 Aug 29.

HS Code	2918990090

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%