MHI-148
Modify Date: 2025-08-25 13:39:13
MHI-148 structure
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Common Name | MHI-148 | ||
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| CAS Number | 172971-76-5 | Molecular Weight | 764.24 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H52ClN2O4.Br | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MHI-148MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and treatment. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1]. |
| Name | MHI-148 |
|---|---|
| Synonym | More Synonyms |
| Description | MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and treatment. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1]. |
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| Related Catalog | |
| In Vitro | MHI-148 (10 µM, 1 h) is significantly more absorbed in HT-29 colon carcinoma cells than in normal NIH3T3 fibroblasts and has tumor imaging and targeting properties[1]. MHI-148 (0-1.5 µM, 3 days) causes only negligible toxicity in HT-29 and NIH3T3 cells[1]. |
| Molecular Formula | C42H52ClN2O4.Br |
|---|---|
| Molecular Weight | 764.24 |
| InChIKey | SBSLCJXMLMGYFH-UHFFFAOYSA-N |
| SMILES | CC1(C)C(=CC=C2CCCC(C=CC3=[N+](CCCCCC(=O)O)c4ccccc4C3(C)C)=C2Cl)N(CCCCCC(=O)O)c2ccccc21.[Br-] |
| Hazard Codes | Xn |
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| MHI-148 |