297730-05-3
297730-05-3 structure
- Name: VX-148
- Chemical Name: (2R)-1-Cyano-2-butanyl [(1S)-1-(3-{[(4-isocyano-3-methoxyphenyl)carbamoyl]amino}phenyl)ethyl]carbamate
- CAS Number: 297730-05-3
- Molecular Formula: C23H25N5O4
- Molecular Weight: 435.476
- Create Date: 2018-07-06 04:29:21
- Modify Date: 2025-08-26 00:22:15
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VX-148 is a potent, uncompetitive, orally bioavailable IMPDH inhibitor with Ki of 6 nM against IMPDH type II enzyme.
| Name | (2R)-1-Cyano-2-butanyl [(1S)-1-(3-{[(4-isocyano-3-methoxyphenyl)carbamoyl]amino}phenyl)ethyl]carbamate |
|---|---|
| Synonyms |
(2R)-1-Cyano-2-butanyl [(1S)-1-(3-{[(4-isocyano-3-methoxyphenyl)carbamoyl]amino}phenyl)ethyl]carbamate
Carbamic acid, N-[(1S)-1-[3-[[[(4-isocyano-3-methoxyphenyl)amino]carbonyl]amino]phenyl]ethyl]-, (1R)-1-(cyanomethyl)propyl ester |
| Molecular Formula | C23H25N5O4 |
|---|---|
| Molecular Weight | 435.476 |
| Exact Mass | 435.190643 |