Imperatoxin A
Imperatoxin A structure
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Common Name | Imperatoxin A | ||
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| CAS Number | 172451-37-5 | Molecular Weight | 3764.4 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C148H260N58O45S6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Imperatoxin AImperatoxin A, a peptide toxin derived from the venom of the African scorpion Pandinus imperator, activator of Ca2+-release channels/ryanodine receptors (RyRs)? enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell[1]. |
| Name | IMPERATOXIN A |
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| Description | Imperatoxin A, a peptide toxin derived from the venom of the African scorpion Pandinus imperator, activator of Ca2+-release channels/ryanodine receptors (RyRs)? enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell[1]. |
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| Related Catalog | |
| Target |
RyRs[1] |
| References |
| Molecular Formula | C148H260N58O45S6 |
|---|---|
| Molecular Weight | 3764.4 |
| Appearance of Characters | lyophilized powder |
| Storage condition | −20°C |
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Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle.
Proc. Natl. Acad. Sci. U. S. A. 89 , 12185-12189, (1992) We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-rel... |
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Peptide probe of ryanodine receptor function. Imperatoxin A, a peptide from the venom of the scorpion Pandinus imperator, selectively activates skeletal-type ryanodine receptor isoforms.
J. Biol. Chem. 270 , 28696-28704, (1995) We have used [3H]ryanodine binding experiments and single channel recordings to provide convergent descriptions of the effect of imperatoxin A (IpTxa), a approximately 5-kDa peptide from the venom of ... |
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Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.
FEBS Lett. 405 , 385-389, (1997) We present the complete amino acid sequence of Imperatoxin A (IpTx(a)), a 33-amino-acid peptide from the venom of the scorpion P. imperator which activates Ca2+ release channels/ryanodine receptors (R... |