欧前胡素A(请核实!)

更新时间:2024-01-30 20:18:32

欧前胡素A(请核实!)结构式
欧前胡素A(请核实!)结构式
品牌特惠专场
常用名 欧前胡素A(请核实!) 英文名 Imperatoxin A
CAS号 172451-37-5 分子量 3764.4
密度 N/A 沸点 N/A
分子式 C148H260N58O45S6 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07
GHS07
信号词 Warning

 欧前胡素A(请核实!)用途


Imperatoxin A,一种源自非洲蝎子 Pandinus imperator 毒液的肽毒素,是 Ca2+-释放通道/兰尼碱受体 (RyRs) 的激活剂,可以促进 Ca2+ 从肌浆网流入细胞。

 欧前胡素A(请核实!)名称

中文名 欧前胡素A(请核实!)
英文名 IMPERATOXIN A

 欧前胡素A(请核实!)生物活性

描述 Imperatoxin A,一种源自非洲蝎子 Pandinus imperator 毒液的肽毒素,是 Ca2+-释放通道/兰尼碱受体 (RyRs) 的激活剂,可以促进 Ca2+ 从肌浆网流入细胞。
相关类别
靶点

RyRs[1]

参考文献

[1]. Georgina B Gurrola, et al. Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca2+-Release Channels/Ryanodine Receptors. Pharmaceuticals (Basel). 2010 Apr 1;3(4):1093-1107.  

 欧前胡素A(请核实!)物理化学性质

分子式 C148H260N58O45S6
分子量 3764.4
外观性状 lyophilized powder
储存条件 −20°C

 欧前胡素A(请核实!)安全信息

符号 GHS07
GHS07
信号词 Warning
危害声明 H302-H312-H332
警示性声明 P280
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xn
风险声明 (欧洲) 20/21/22
安全声明 (欧洲) 7-9-36/37
危险品运输编码 NONH for all modes of transport
WGK德国 3

 欧前胡素A(请核实!)文献3

更多文献
Scorpion toxins targeted against the sarcoplasmic reticulum Ca(2+)-release channel of skeletal and cardiac muscle.

Proc. Natl. Acad. Sci. U. S. A. 89 , 12185-12189, (1992)

We report the purification of two peptides, called "imperatoxin inhibitor" and "imperatoxin activator," from the venom of the scorpion Pandinus imperator targeted against ryanodine receptor Ca(2+)-rel...

Peptide probe of ryanodine receptor function. Imperatoxin A, a peptide from the venom of the scorpion Pandinus imperator, selectively activates skeletal-type ryanodine receptor isoforms.

J. Biol. Chem. 270 , 28696-28704, (1995)

We have used [3H]ryanodine binding experiments and single channel recordings to provide convergent descriptions of the effect of imperatoxin A (IpTxa), a approximately 5-kDa peptide from the venom of ...

Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.

FEBS Lett. 405 , 385-389, (1997)

We present the complete amino acid sequence of Imperatoxin A (IpTx(a)), a 33-amino-acid peptide from the venom of the scorpion P. imperator which activates Ca2+ release channels/ryanodine receptors (R...