oritavancin

Modify Date: 2024-01-02 12:54:42

oritavancin Structure
oritavancin structure
Common Name oritavancin
CAS Number 171099-57-3 Molecular Weight 1793.10000
Density N/A Boiling Point N/A
Molecular Formula C86H97Cl3N10O26 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of oritavancin


Oritavancin (LY 333328) is an orally active glycopeptide antibiotic with activity against gram-positive organisms. Oritavancin shows antibacterial effect against multidrug-resistant S. pneumoniae. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential[1][2].

 Names

Name oritavancin
Synonym More Synonyms

 oritavancin Biological Activity

Description Oritavancin (LY 333328) is an orally active glycopeptide antibiotic with activity against gram-positive organisms. Oritavancin shows antibacterial effect against multidrug-resistant S. pneumoniae. Oritavancin inhibits cell wall synthesis and disrupts the membrane potential[1][2].
Related Catalog
References

[1]. Coyle EA, et al. Activity of oritavancin (LY333328), an investigational glycopeptide, compared to that of vancomycin against multidrug-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model. Antimicrob Agents Chemother. 2001 Mar;45(3):706-9.

[2]. Arhin FF, et al. Effect of polysorbate 80 on oritavancin binding to plastic surfaces: implications for susceptibility testing. Antimicrob Agents Chemother. 2008 May;52(5):1597-603.

 Chemical & Physical Properties

Molecular Formula C86H97Cl3N10O26
Molecular Weight 1793.10000
Exact Mass 1790.56000
PSA 560.98000
LogP 8.57000

 Safety Information

Hazard Codes Xn

 Synonyms

LY333328
Orbactiv
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