EGLU
Modify Date: 2025-09-17 23:03:20
EGLU structure
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Common Name | EGLU | ||
|---|---|---|---|---|
| CAS Number | 170984-72-2 | Molecular Weight | 175.18200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H13NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EGLUEGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1]. |
| Name | (2S)-2-amino-2-ethylpentanedioic acid |
|---|---|
| Synonym | More Synonyms |
| Description | EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1]. |
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| Related Catalog | |
| In Vitro | EGLU (200 μM) selectively antagonizes (lS,3S)-ACPD-induced depressions of the monosynaptic component of the DRVRP, displaying little or no antagonist activity versus L-AP6 induced depressions or on the DRVRP alone[1]. |
| References |
| Molecular Formula | C7H13NO4 |
|---|---|
| Molecular Weight | 175.18200 |
| Exact Mass | 175.08400 |
| PSA | 100.62000 |
| LogP | 0.74360 |
| InChIKey | QFYBYZLHPIALCZ-ZETCQYMHSA-N |
| SMILES | CCC(N)(CCC(=O)O)C(=O)O |
| EGLU |
| Tocris-0971 |
| L-Glutamic acid,2-ethyl |