CD38 inhibitor 78c

Modify Date: 2024-01-04 20:18:26

CD38 inhibitor 78c structure	Common Name	CD38 inhibitor 78c
	CAS Number	1700637-55-3	Molecular Weight	413.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₇N₃O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CD38 inhibitor 78c

CD38 inhibitor 1 is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].

Name	CD38 inhibitor 1

Description	CD38 inhibitor 1 is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle[1]. Animal Model: Diet induced obese (DIO) C57Bl6 mice[1] Dosage: 30 mg/kg Administration: Orally once Result: NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
References	[1]. Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71.

Molecular Formula	C₂₂H₂₇N₃O₃S
Molecular Weight	413.53

DC Chemicals Limited
China
Product Name: CD38 inhibitor 78c
Price: $800.0/100mg $1400.0/250mg $2800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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