Obtusifoliol
Modify Date: 2024-01-10 11:02:44
Obtusifoliol structure
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Common Name | Obtusifoliol | ||
|---|---|---|---|---|
| CAS Number | 16910-32-0 | Molecular Weight | 426.71700 | |
| Density | 0.98g/cm3 | Boiling Point | 501.3ºC at 760mmHg | |
| Molecular Formula | C30H50O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 221.9ºC | |
Use of ObtusifoliolObtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with Kd values of 1.2 µM and 1.4 µM for Trypanosoma brucei (TB) and human CYP51, respectively[1]. |
| Name | obtusifoliol |
|---|---|
| Synonym | More Synonyms |
| Description | Obtusifoliol is a specific CYP51 inhibitor, Obtusifoliol shows the affinity with Kd values of 1.2 µM and 1.4 µM for Trypanosoma brucei (TB) and human CYP51, respectively[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Obtusifoliol (0.1-100 µM; 48 hours) inhibit MCF-7 and MDA-MB231 breast cancer cells proliferation via arresting cell cycle progression and induction of apoptosis[1]. Cell Viability Assay[2] Cell Line: MCF-7; MDA-MB231 breast cancer cells Concentration: 0.1, 1, 10, 40, 80, and 100 µM Incubation Time: 48 hours Result: Inhibited MCF-7 and MDA-MB231 breast cancer cells proliferation. |
| References |
| Density | 0.98g/cm3 |
|---|---|
| Boiling Point | 501.3ºC at 760mmHg |
| Molecular Formula | C30H50O |
| Molecular Weight | 426.71700 |
| Flash Point | 221.9ºC |
| Exact Mass | 426.38600 |
| PSA | 20.23000 |
| LogP | 8.33500 |
| Vapour Pressure | 3.77E-12mmHg at 25°C |
| Index of Refraction | 1.525 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
|---|
| 4alpha,14alpha-Dimethyl-5alpha-ergosta-8,24(28)-dien-3beta-ol |
| (3S,4S,5S,10S,13R,14R,17R)-4,10,13,14-tetramethyl-17-[(2R)-6-methyl-5-methylideneheptan-2-yl]-1,2,3,4,5,6,7,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol |
| 4alpha,14alpha-Dimethyl-24-methylene-5alpha-cholesta-8-en-3beta-ol |
| EECD77B7-C927-4E6E-B634-DEDFB042A6B9 |
| methylsterol |
| Obtusifoliol |