I-191

Modify Date: 2025-08-25 08:15:52

I-191 structure	Common Name	I-191
	CAS Number	1690172-25-8	Molecular Weight	423.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₆FN₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of I-191

I-191 is a protease-activated receptor 2 (PAR-2) signaling pathway inhibitor extracted from patent WO2015048245A1. I-191 inhibits PAR-2 activators such as SLIGKV, Trypsin, and Thrombin with IC50s of 0.0014 μM, 0.0023 μM, 0.32 μM, respectively[1].

Name	I-191

Description	I-191 is a protease-activated receptor 2 (PAR-2) signaling pathway inhibitor extracted from patent WO2015048245A1. I-191 inhibits PAR-2 activators such as SLIGKV, Trypsin, and Thrombin with IC50s of 0.0014 μM, 0.0023 μM, 0.32 μM, respectively[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR) Research Areas >> Inflammation/Immunology
Target	IC50: 0.0014 μM (SLIGKV), 0.0023 μM (Trypsin), 0.32 μM (Thrombin)[1]
References	[1]. Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO2015048245A1.

Molecular Formula	C₂₃H₂₆FN₅O₂
Molecular Weight	423.48
InChIKey	DTASTQAQBOZSRR-UHFFFAOYSA-N
SMILES	CC(C)(C)c1cc(-c2ccc(F)cc2)nn2cc(C(=O)N3CCNC(=O)C3(C)C)nc12

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: I-191
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: I-191
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: I-191
Price: $750.0/100mg $1200.0/250mg $2400.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.