I-SAP
Modify Date: 2025-08-23 10:42:38
I-SAP structure
|
Common Name | I-SAP | ||
|---|---|---|---|---|
| CAS Number | 133538-58-6 | Molecular Weight | 531.447 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 606.3±61.0 °C at 760 mmHg | |
| Molecular Formula | C22H30INO4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 320.5±33.2 °C | |
Use of I-SAPI-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC)[1][2]. |
| Name | (E)-7-[3-[(4-iodophenyl)sulfonylamino]-6,6-dimethyl-4-bicyclo[3.1.1]heptanyl]hept-5-enoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | I-SAP is a radioiodinated TXA2/PGH2 receptor antagonist. The bind between I-SAP and the receptors, is inhibited by the histidine modifying reagent diethyl-pyrocarbonate (DEPC)[1][2]. |
|---|---|
| Related Catalog | |
| Target |
TXA2 Receptor |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 606.3±61.0 °C at 760 mmHg |
| Molecular Formula | C22H30INO4S |
| Molecular Weight | 531.447 |
| Flash Point | 320.5±33.2 °C |
| Exact Mass | 531.093994 |
| PSA | 91.85000 |
| LogP | 6.37 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.623 |
| InChIKey | SZNMERGTFJHNSM-JAWYFFTGSA-N |
| SMILES | CC1(C)C2CC(NS(=O)(=O)c3ccc(I)cc3)C(CC=CCCCC(=O)O)C1C2 |
| 5-Heptenoic acid, 7-[(1S,2S,3S,5R)-3-[[(4-iodophenyl)sulfonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-, (5Z)- |
| Isap acid |
| I-SAP |
| (5Z)-7-[(1S,2S,3S,5R)-3-{[(4-Iodophenyl)sulfonyl]amino}-6,6-dimethylbicyclo[3.1.1]hept-2-yl]-5-heptenoic acid |