Tetrazine-Ph-PEG5-NHS ester structure
|
Common Name | Tetrazine-Ph-PEG5-NHS ester | ||
|---|---|---|---|---|
| CAS Number | 1682653-80-0 | Molecular Weight | 604.609 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C27H36N6O10 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tetrazine-Ph-PEG5-NHS esterTetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | Tetrazine-PEG5-NHS ester |
|---|---|
| Synonym | More Synonyms |
| Description | Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H36N6O10 |
| Molecular Weight | 604.609 |
| Exact Mass | 604.249268 |
| LogP | -4.14 |
| Index of Refraction | 1.570 |
| 19-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-19-oxo-N-[4-(1,2,4,5-tetrazin-3-yl)benzyl]-4,7,10,13,16-pentaoxanonadecan-1-amide |
| Tz-PEG5-NHS |
| 4,7,10,13,16-Pentaoxanonadecan-1-amide, 19-[(2,5-dioxo-1-pyrrolidinyl)oxy]-19-oxo-N-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methyl]- |
| MFCD28505547 |
| Tetrazine-PEG5-NHS ester |