BMT-124110
Modify Date: 2024-01-10 22:26:40
BMT-124110 structure
|
Common Name | BMT-124110 | ||
|---|---|---|---|---|
| CAS Number | 1679371-59-5 | Molecular Weight | 369.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMT-124110BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively[1]. |
| Name | BMT-124110 |
|---|
| Description | BMT-124110 is a potent, selective AAK1 inhibitor with an IC50 of 0.9 nM. BMT-124110 shows antinociceptive activity. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 17 and 99 nM, respectively[1]. |
|---|---|
| Related Catalog | |
| In Vitro | BMT-124110 shows a cellular IC50 of 3.2±1.4 nM for AAK1[1]. |
| In Vivo | BMT-124110 is added directly onto the spinal corevd by microiontophoresis, leading to reduction in windup-induced activity in 10 of 14 animals[1]. |
| References |
| Molecular Formula | C21H27N3O3 |
|---|---|
| Molecular Weight | 369.46 |