1-(4-Methoxyphenyl)cyclopropanecarboxylic acid

Modify Date: 2024-01-10 18:53:32

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid Structure
1-(4-Methoxyphenyl)cyclopropanecarboxylic acid structure
Common Name 1-(4-Methoxyphenyl)cyclopropanecarboxylic acid
CAS Number 16728-01-1 Molecular Weight 192.211
Density 1.3±0.1 g/cm3 Boiling Point 347.7±35.0 °C at 760 mmHg
Molecular Formula C11H12O3 Melting Point 127-132 °C
MSDS N/A Flash Point 138.6±19.4 °C

 Names

Name 1-(4-Methoxyphenyl)cyclopropanecarboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 347.7±35.0 °C at 760 mmHg
Melting Point 127-132 °C
Molecular Formula C11H12O3
Molecular Weight 192.211
Flash Point 138.6±19.4 °C
Exact Mass 192.078644
PSA 46.53000
LogP 1.46
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.585
Storage condition Room temperature.

 MSDS

Name: 1-(4-Methoxyphenyl)-1-cyclopropanecarboxylic acid 97% Material Safety Data Sheet
Synonym: 1-(4-Methoxyphenyl)cyclopropane-1-carboxylic aci
CAS: 16728-01-1
Section 1 - Chemical Product MSDS Name:1-(4-Methoxyphenyl)-1-cyclopropanecarboxylic acid 97% Material Safety Data Sheet
Synonym:1-(4-Methoxyphenyl)cyclopropane-1-carboxylic aci

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
16728-01-1 1-(4-Methoxyphenyl)-1-cyclopropanecarb 97 240-788-5
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable container for disposal. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 16728-01-1: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 124.00 - 126.00 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: C11H12O3
Molecular Weight: 192.21

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 16728-01-1 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1-(4-Methoxyphenyl)-1-cyclopropanecarboxylic acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 16728-01-1: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 16728-01-1 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 16728-01-1 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Safety Phrases S24/25
HS Code 2918990090

 Synthetic Route

~77%

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid Structure

1-(4-Methoxyphe...

CAS#:16728-01-1

Literature: Mndzhoyan, Sh. L.; Tsinker, M. G.; Ovakimyan, A. R.; Ter-Zakharyan, Yu. Z.; Kazaryan, E. V.; Paronikyan, R. V. Pharmaceutical Chemistry Journal, 1980 , vol. 14, # 2 p. 114 - 118 Khimiko-Farmatsevticheskii Zhurnal, 1980 , vol. 14, # 2 p. 40 - 45

~62%

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid Structure

1-(4-Methoxyphe...

CAS#:16728-01-1

Literature: Kirmse, Wolfgang; Rode, Jutta Chemische Berichte, 1986 , vol. 119, # 12 p. 3694 - 3703

~%

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid Structure

1-(4-Methoxyphe...

CAS#:16728-01-1

Literature: Chemische Berichte, , vol. 119, # 12 p. 3694 - 3703

~%

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid Structure

1-(4-Methoxyphe...

CAS#:16728-01-1

Literature: Chemische Berichte, , vol. 119, # 12 p. 3694 - 3703

~%

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid Structure

1-(4-Methoxyphe...

CAS#:16728-01-1

Literature: Pharmaceutical Chemistry Journal, , vol. 14, # 2 p. 114 - 118 Khimiko-Farmatsevticheskii Zhurnal, , vol. 14, # 2 p. 40 - 45

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

1-(4-Methoxyphenyl)cyclopropanecarboxylic acid
1-(4-methoxyphenyl)cyclopropane-1-carboxylic acid
EINECS 240-788-5
MFCD00019223
Cyclopropanecarboxylic acid, 1-(4-methoxyphenyl)-
1-(4-Methoxyphenyl)-1-cyclopropanecarboxylic acid
Cyclopropanecarboxylicacid, 1-(4-methoxyphenyl)-