4-Formamidoantipyrine
4-Formamidoantipyrine structure
|
Common Name | 4-Formamidoantipyrine | ||
|---|---|---|---|---|
| CAS Number | 1672-58-8 | Molecular Weight | 231.251 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 374.5±52.0 °C at 760 mmHg | |
| Molecular Formula | C12H13N3O2 | Melting Point | 189-192ºC | |
| MSDS | Chinese USA | Flash Point | 180.3±30.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 4-Formamidoantipyrine4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1]. |
| Name | 4-formylaminoantipyrine |
|---|---|
| Synonym | More Synonyms |
| Description | 4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 374.5±52.0 °C at 760 mmHg |
| Melting Point | 189-192ºC |
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | 231.251 |
| Flash Point | 180.3±30.7 °C |
| Exact Mass | 231.100784 |
| PSA | 56.03000 |
| LogP | 0.41 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.609 |
| InChIKey | WSJBSKRPKADYRQ-UHFFFAOYSA-N |
| SMILES | Cc1c(NC=O)c(=O)n(-c2ccccc2)n1C |
| Storage condition | Refrigerator |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Phrases | 20/22 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933199090 |
|
~77%
4-Formamidoanti... CAS#:1672-58-8 |
| Literature: Lopez-Munoz, Francisco Javier; Soria-Arteche, Olivia; Lopez, Jose Raul Medina; Hurtado Y De La Pena, Marcela; Garcia, Ma. Concepcion Lozada; Moreno-Rocha, Luis Alfonso; Dominguez-Ramirez, Adriana Miriam Drug Development Research, 2013 , vol. 74, # 5 p. 332 - 338 |
|
~%
4-Formamidoanti... CAS#:1672-58-8 |
| Literature: Justus Liebigs Annalen der Chemie, , vol. 293, p. 66 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933199090 |
|---|---|
| Summary | 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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High-performance liquid chromatographic assay for metamizol metabolites in rat plasma: application to pharmacokinetic studies.
J. Pharm. Biomed. Anal. 71 , 173-8, (2012) In order to evaluate the pharmacokinetics of metamizol in the presence of morphine in arthritic rats, after subcutaneous administration of the drugs, an easy, rapid, sensitive and selective analytical... |
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Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis-B virus does not occur in rapid acetylators.
Eur. J. Clin. Pharmacol. 57(6-7) , 461-5, (2001) We previously found that, compared with healthy subjects. asymptomatic hepatitis-B virus (HBV) carriers displaying slow acetylator phenotype demonstrate a significant prolongation of the elimination h... |
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Simple high-performance liquid chromatographic method for simultaneous determination of aminopyrine and its metabolites.
J. Chromatogr. A. 421(1) , 198-205, (1987)
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| 4-formylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one |
| N-(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)formamide |
| N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide |
| N-(2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)carboxamide |
| (1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)imidoformic acid |
| 4-Formylaminoantipyrine |
| Methanimidic acid, (2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- |
| 1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-ylformamide |
| 4-Formamidoantipyrine |
| Formamide,N-antipyrinyl |
| N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)formamide |
| 4-formyl-aminoantipyrin |
| Formamide, N-(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)- |
| 4-Formylaminoantipyrine (N-(1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)formamide |
| 4-formaminoantipyrine |
| N-Formyl-4-aminoantipyrine |
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- Shanghai Nianxing Industrial Co., Ltd
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- Product Name: 4-Formamidoantipyrine
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