cis-Mulberroside A
Modify Date: 2024-01-09 23:39:43
cis-Mulberroside A structure
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Common Name | cis-Mulberroside A | ||
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| CAS Number | 166734-06-1 | Molecular Weight | 568.524 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 954.7±65.0 °C at 760 mmHg | |
| Molecular Formula | C26H32O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 531.2±34.3 °C | |
Use of cis-Mulberroside Acis-Mulberroside A (Mulberroside D) is the cis-isomer of Mulberroside A. Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.)[1]. Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects[2]. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM[3]. |
| Name | 3-{(Z)-2-[4-(β-D-Glucopyranosyloxy)-2-hydroxyphenyl]vinyl}-5-hydroxyphenyl β-D-glucopyranoside |
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| Synonym | More Synonyms |
| Description | cis-Mulberroside A (Mulberroside D) is the cis-isomer of Mulberroside A. Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.)[1]. Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory antiapoptotic effects[2]. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM[3]. |
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| Related Catalog | |
| In Vivo | Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic mice[4]. Animal Model: Male Kun-Ming mice (20±2 g)[4] Dosage: 5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight Administration: Orally initiated at 9:00 a.m. Result: 10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 954.7±65.0 °C at 760 mmHg |
| Molecular Formula | C26H32O14 |
| Molecular Weight | 568.524 |
| Flash Point | 531.2±34.3 °C |
| Exact Mass | 568.179199 |
| LogP | -1.16 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.742 |
| Hazard Codes | Xi |
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| 3-{(Z)-2-[4-(β-D-Glucopyranosyloxy)-2-hydroxyphenyl]vinyl}-5-hydroxyphenyl β-D-glucopyranoside |
| β-D-Glucopyranoside, 3-[(Z)-2-[4-(β-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl |
| cis-Mulberroside A |