Neotame

Modify Date: 2025-08-20 18:26:48

Neotame structure	Common Name	Neotame
	CAS Number	165450-17-9	Molecular Weight	378.463
	Density	1.1±0.1 g/cm3	Boiling Point	535.8±60.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₀N₂O₅	Melting Point	80.9-83.4ºC
	MSDS	Chinese USA	Flash Point	277.9±32.9 °C

Use of Neotame

Neotame is a derivative of Aspartame and is a low-caloric and high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame is a non-nutritive sweetener and flavor enhancer that can be used in a variety of foods[1][2].

Name	neotame
Synonym	More Synonyms

Description	Neotame is a derivative of Aspartame and is a low-caloric and high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame is a non-nutritive sweetener and flavor enhancer that can be used in a variety of foods[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Liang Chi, et al. Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules. 2018 Feb 9;23(2):367. [2]. Anuradha Kumari, et al. Stability of Aspartame and Neotame in Pasteurized and In-Bottle Sterilized Flavoured Milk. Food Chem. 2016 Apr 1;196:533-8.

Description

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Liang Chi, et al. Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules. 2018 Feb 9;23(2):367.

[2]. Anuradha Kumari, et al. Stability of Aspartame and Neotame in Pasteurized and In-Bottle Sterilized Flavoured Milk. Food Chem. 2016 Apr 1;196:533-8.

Density	1.1±0.1 g/cm3
Boiling Point	535.8±60.0 °C at 760 mmHg
Melting Point	80.9-83.4ºC
Molecular Formula	C₂₀H₃₀N₂O₅
Molecular Weight	378.463
Flash Point	277.9±32.9 °C
Exact Mass	378.215485
PSA	104.73000
LogP	4.73
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.530

Neotame MSDS(Chinese)

Safety Phrases	24/25
RIDADR	NONH for all modes of transport
HS Code	2924299090

3,3-Dimethylbutanal

CAS#:2987-16-8

Aspartame

CAS#:22839-47-0

~87%

Neotame

CAS#:165450-17-9

Literature: Ajinomoto Co., Inc. Patent: US6914151 B1, 2005 ; Location in patent: Page/Page column 5-6 ;

Precursor 2
CAS#:2987-16-8 3,3-Dimethylbutanal CAS#:22839-47-0 Aspartame
DownStream 0

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Methyl N-(3,3-dimethylbutyl)-L-α-aspartyl-L-phenylalaninate

UNII-VJ597D52EX

(3S)-3-(3,3-dimethylbutylamino)-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid

(3S,4E)-3-[(3,3-Dimethylbutyl)amino]-4-hydroxy-4-{[(2S)-1-methoxy-1-oxo-3-phenyl-2-propanyl]imino}butanoic acid

L-Phenylalanine, N-[(2S)-3-carboxy-2-[(3,3-dimethylbutyl)amino]-1-hydroxypropylidene]-, methyl ester, (E)-

Neotame

Methyl N-(3,3-dimethylbutyl)-L-α-aspartylphenylalaninate

E961

L-phenylalanine, N-(3,3-dimethylbutyl)-L-α-aspartyl-, methyl ester

N-(3,3-Dimethylbutyl)-L-a-aspartyl-L-phenylalanine Methyl Ester

VJ597D52EX

N-(3,3-dimethylbutyl)-L-aspartyl-L-phenylalanine methyl ester

Phenylalanine, N-(3,3-dimethylbutyl)-L-α-aspartyl-, methyl ester

(S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic ac

N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine methyl ester

(S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Neotame
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Neotame
Price: ￥218.0/5g
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Neotame
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-[N-(3,3-Dimethylbutyl)-L-aspartyl]-L-phenylalanine 1-methyl ester
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Neotame
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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Price: ￥36.3/5g

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Neotame

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