THZ-2-118
Modify Date: 2024-04-08 10:37:12
THZ-2-118 structure
|
Common Name | THZ-2-118 | ||
|---|---|---|---|---|
| CAS Number | 1644498-54-3 | Molecular Weight | 493.571 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H27N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of THZ-2-118THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM;THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM). |
| Name | THZ-2-118 |
|---|
| Description | THZ-2-118 is a potent selective inhibitor of IRAK1 with IC50 of 14.2 nM;THZ-2-118 does not inhibitor IRAK4 at 10 uM, also potently inhibits JNK1/2/3 (IC50=1-2 nM). |
|---|---|
| References | 1. Hatcher JM, et al. ACS Med Chem Lett. 2020 Oct 9;11(11):2238-2243. |
| Molecular Formula | C28H27N7O2 |
|---|---|
| Molecular Weight | 493.571 |