SAFit1

Modify Date: 2025-09-26 15:56:19

SAFit1 structure	Common Name	SAFit1
	CAS Number	1643125-32-9	Molecular Weight	747.87
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₅₃NO₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SAFit1

SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM[1][2].

Name	SAFit1

Description	SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
Target	Ki: 4±0.3 nM (FKBP51), >50000 nM (FKBP52)[1]
In Vitro	SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons. SAFit1 is active over a wide concentration range[1].
References	[1]. Gaali S, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nat Chem Biol. 2015 Jan;11(1):33-7. [2]. Sidibeh CO, et al. FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes. Endocrine. 2018 Oct;62(1):116-128.

Molecular Formula	C₄₂H₅₃NO₁₁
Molecular Weight	747.87
InChIKey	OEQZPFWOEOOISR-AKTKKGGCSA-N
SMILES	COc1ccc(CCC(OC(=O)C2CCCCN2C(=O)C(c2cc(OC)c(OC)c(OC)c2)C2CCCCC2)c2cccc(OCC(=O)O)c2)cc1OC
Storage condition	2-8℃

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SAFit1?
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: SAFit1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

SAFit1 suppliers

Price: ￥4500/5 mg

Reference only. check more SAFit1 price