SAFit1

Modify Date: 2024-01-19 04:03:04

SAFit1 structure	Common Name	SAFit1
	CAS Number	1643125-32-9	Molecular Weight	747.87
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₂H₅₃NO₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SAFit1

SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM[1][2].

Name	SAFit1

Description	SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
Target	Ki: 4±0.3 nM (FKBP51), >50000 nM (FKBP52)[1]
In Vitro	SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons. SAFit1 is active over a wide concentration range[1].
References	[1]. Gaali S, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nat Chem Biol. 2015 Jan;11(1):33-7. [2]. Sidibeh CO, et al. FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes. Endocrine. 2018 Oct;62(1):116-128.

Molecular Formula	C₄₂H₅₃NO₁₁
Molecular Weight	747.87
Storage condition	2-8℃

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SAFit1?
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: SAFit1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: ￥4500/5 mg

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