ML303
Modify Date: 2024-01-31 10:04:21
ML303 structure
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Common Name | ML303 | ||
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| CAS Number | 1638211-04-7 | Molecular Weight | 399.37 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H16F3N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ML303ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1[1]. |
| Name | ML303 |
|---|
| Description | ML303 is a pyrazolopyridine influenza virus nonstructural protein 1 (NS1) antagonist (IC90 = 155 nM), with an EC50 of 0.7 μM for Influenza A virus H1N1[1]. |
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| Related Catalog | |
| Target |
EC50: 0.7 μM (H1N1)[1]. |
| In Vitro | ML303 (20 μM, 6 h) treatment restore IFN-β mRNA levels in MDCK cells[1]. Western Blot Analysis[1] Cell Line: MDCK cells infected with A/PR/8/34, at a MOI of 2, for 6 hours. Concentration: 20 μM. Incubation Time: 6 hours. Result: Restored IFN-β mRNA levels in MDCK cells. |
| References |
| Molecular Formula | C21H16F3N3O2 |
|---|---|
| Molecular Weight | 399.37 |
| Storage condition | -20°C |