Biotinylated-JQ1

Modify Date: 2025-08-22 00:14:43

Biotinylated-JQ1 Structure
Biotinylated-JQ1 structure
Common Name Biotinylated-JQ1
CAS Number 1635437-52-3 Molecular Weight 829.47
Density N/A Boiling Point N/A
Molecular Formula C39H53ClN8O6S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotinylated-JQ1


Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1].

 Names

Name Biotinylated-JQ1

 Biotinylated-JQ1 Biological Activity

Description Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1].
Related Catalog
In Vitro Biotinylated-JQ1 (0.1 nM-100 μM; 72 hours) inhibits MM1.S cell proliferation with an EC50 of 0.4 μM[1].
References

[1]. Lars Anders, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014 Jan;32(1):92-6.

 Chemical & Physical Properties

Molecular Formula C39H53ClN8O6S2
Molecular Weight 829.47
InChIKey HLZRRKIVMLXYEU-MSMWPWNWSA-N
SMILES Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC1SCC3NC(=O)NC31)c1nnc(C)n1-2
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