Biotinylated-JQ1 structure
|
Common Name | Biotinylated-JQ1 | ||
|---|---|---|---|---|
| CAS Number | 1635437-52-3 | Molecular Weight | 829.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C39H53ClN8O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Biotinylated-JQ1Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1]. |
| Name | Biotinylated-JQ1 |
|---|
| Description | Biotinylated-JQ1 (Biotin-JQ1) is a biotinylated derivative of JQ1 with high affinity for the bromodomain of BRD4. Biotinylated-JQ1 inhibits MM1.S multiple myeloma cells proliferation with the EC50 of 0.4 μM[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Biotinylated-JQ1 (0.1 nM-100 μM; 72 hours) inhibits MM1.S cell proliferation with an EC50 of 0.4 μM[1]. |
| References |
| Molecular Formula | C39H53ClN8O6S2 |
|---|---|
| Molecular Weight | 829.47 |
| InChIKey | HLZRRKIVMLXYEU-MSMWPWNWSA-N |
| SMILES | Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC1SCC3NC(=O)NC31)c1nnc(C)n1-2 |