Praliciguat

Modify Date: 2025-08-26 18:05:54

Praliciguat Structure
Praliciguat structure
Common Name Praliciguat
CAS Number 1628730-49-3 Molecular Weight 534.36
Density N/A Boiling Point N/A
Molecular Formula C21H14F8N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Praliciguat


Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].

 Names

Name Praliciguat

 Praliciguat Biological Activity

Description Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].
Related Catalog
Target

EC50: 197 nM (sGC)[1]

References

[1]. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.

 Chemical & Physical Properties

Molecular Formula C21H14F8N6O2
Molecular Weight 534.36
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