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1628730-49-3

1628730-49-3 structure
1628730-49-3 structure
  • Name: Praliciguat
  • Chemical Name: Praliciguat
  • CAS Number: 1628730-49-3
  • Molecular Formula: C21H14F8N6O2
  • Molecular Weight: 534.36
  • Catalog: Signaling Pathways GPCR/G Protein Guanylate Cyclase
  • Create Date: 2019-06-02 11:16:56
  • Modify Date: 2024-01-02 07:35:33
  • Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].

Name Praliciguat
Description Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].
Related Catalog
Target

EC50: 197 nM (sGC)[1]

References

[1]. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.

Molecular Formula C21H14F8N6O2
Molecular Weight 534.36