1628730-49-3

1628730-49-3 structure

Name: Praliciguat
Chemical Name: Praliciguat
CAS Number: 1628730-49-3
Molecular Formula: C₂₁H₁₄F₈N₆O₂
Molecular Weight: 534.36
Catalog: Signaling Pathways GPCR/G Protein Guanylate Cyclase
Create Date: 2019-06-02 11:16:56
Modify Date: 2025-08-26 18:05:54
Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].

Name	Praliciguat

Description	Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase
Target	EC50: 197 nM (sGC)[1]
References	[1]. Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.

Molecular Formula	C₂₁H₁₄F₈N₆O₂
Molecular Weight	534.36