Polygalaxanthone III

Modify Date: 2025-08-25 18:10:11

Polygalaxanthone III structure	Common Name	Polygalaxanthone III
	CAS Number	162857-78-5	Molecular Weight	568.481
	Density	1.83	Boiling Point	973.2±65.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₂₈O₁₅	Melting Point	180-183℃
	MSDS	N/A	Flash Point	327.7±27.8 °C

Use of Polygalaxanthone III

Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].

Name	Polygalaxanthone III
Synonym	More Synonyms

Description	Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Inflammation/Immunology
References	[1]. Li ZL, et al. Effect of oligosaccharide esters and polygalaxanthone Ill from Polygala tenuifolia willd towards cytochrome P450. Zhongguo Zhong Yao Za Zhi. 2014 Nov;39(22):4459-63.

Density	1.83
Boiling Point	973.2±65.0 °C at 760 mmHg
Melting Point	180-183℃
Molecular Formula	C₂₅H₂₈O₁₅
Molecular Weight	568.481
Flash Point	327.7±27.8 °C
Exact Mass	568.142822
LogP	-0.31
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.765

Safety Phrases	S24/25

D-Glucitol, 1,5-anhydro-6-O-[(2R,3R,4R)-tetrahydro-3,4-dihydroxy-4-(hydroxymethyl)-2-furanyl]-1-C-(1,3,6-trihydroxy-7-methoxy-9-oxo-9H-xanthen-2-yl)-, (1S)-

(1S)-1,5-Anhydro-6-O-[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-1-(1,3,6-trihydroxy-7-methoxy-9-oxo-9H-xanthen-2-yl)-D-glucitol

polygalaxanthone III