DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt

Modify Date: 2024-01-13 18:21:38

DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt structure	Common Name	DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
	CAS Number	161877-70-9	Molecular Weight	1233.39
	Density	1.38g/cm3	Boiling Point	N/A
	Molecular Formula	C₆₁H₇₆N₁₂O₁₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt

Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].

Name	Caspase 1 (ICE) substrate for FRET assays,DABCYL-YVADAPV-EDANS
Synonym	More Synonyms

Description	Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].
Related Catalog	Research Areas >> Others
References	[1]. Schulz JB, et al. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci. 1996 Aug 1;16(15):4696-706.

Density	1.38g/cm3
Molecular Formula	C₆₁H₇₆N₁₂O₁₄S
Molecular Weight	1233.39
Exact Mass	1232.53000
PSA	384.28000
LogP	7.91240
Index of Refraction	1.654