161877-70-9

161877-70-9 structure

Name: DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
Chemical Name: Caspase 1 (ICE) substrate for FRET assays,DABCYL-YVADAPV-EDANS
CAS Number: 161877-70-9
Molecular Formula: C₆₁H₇₆N₁₂O₁₄S
Molecular Weight: 1233.39
Catalog: Research Areas Others
Create Date: 2018-10-20 13:33:57
Modify Date: 2025-08-23 12:30:38
Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].

Name	Caspase 1 (ICE) substrate for FRET assays,DABCYL-YVADAPV-EDANS
Synonyms	DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS INTERLEUKIN-1BETA CONVERTING ENZYME SUBSTRATE II ICE SUBSTRATE II PASE 1 (ICE) SUBSTRATE 4-(4'-dimethylaminophenylazo)benzoyl-tyrosyl-valyl-alanyl-aspartyl-alanyl-prolyl-valyl-5((2-aminoethyl)amino)naphthalene-1-sulfonic acid DABCYL-YVADAPV-EDANS 4-(4-DIMETHYLAMINOPHENYLAZO)BENZOYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-5-[(2-AMINOETHYL)AMINO]-NAPHTHALENE-1-SULFONIC ACID Caspase 1 (ICE) substrate for FRET assays IL-1B CONVERTING ENZYME SUBSTRATE II

Description	Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].
Related Catalog	Research Areas >> Others
References	[1]. Schulz JB, et al. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci. 1996 Aug 1;16(15):4696-706.