Lupeol acetate

Modify Date: 2024-01-02 12:40:51

Lupeol acetate structure	Common Name	Lupeol acetate
	CAS Number	1617-68-1	Molecular Weight	468.75400
	Density	1.01g/cm3	Boiling Point	502.7ºC at 760mmHg
	Molecular Formula	C₃₂H₅₂O₂	Melting Point	218ºC
	MSDS	N/A	Flash Point	254.7ºC

Use of Lupeol acetate

Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].

Name	[(1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-yl] acetate
Synonym	More Synonyms

Description	Lupeol acetate, a derivative of Lupeol, suppresses the progression of rheumatoid arthritis (RA) by inhibiting the activation of macrophages and osteoclastogenesis through downregulations of TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Wang WH, et al. Lupeol acetate ameliorates collagen-induced arthritis and osteoclastogenesis of mice through improvement of microenvironment. Biomed Pharmacother. 2016;79:231-240.

Density	1.01g/cm3
Boiling Point	502.7ºC at 760mmHg
Melting Point	218ºC
Molecular Formula	C₃₂H₅₂O₂
Molecular Weight	468.75400
Flash Point	254.7ºC
Exact Mass	468.39700
PSA	26.30000
LogP	8.59560
Vapour Pressure	3.1E-10mmHg at 25°C
Index of Refraction	1.524