Taniborbactam

Modify Date: 2025-08-25 12:39:00

Taniborbactam Structure
Taniborbactam structure
Common Name Taniborbactam
CAS Number 1613267-49-4 Molecular Weight 389.25
Density N/A Boiling Point N/A
Molecular Formula C19H28BN3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Taniborbactam


Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].

 Names

Name Taniborbactam

 Taniborbactam Biological Activity

Description Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].
Related Catalog
Target

IC50: <100 nM (SHV-5 β-lactamase), <100 nM (KPC-2 β-lactamase), <100 nM (VIM-2 β-lactamase), <100 nM (AmpC β-lactamase), 0.1 to 1 μM (OXA-1 β-lactamase)[1]

In Vitro Taniborbactam (Example 15) is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1].
References

[1]. Christopher J. Burns, et al. Beta-lactamase inhibitors. WO2014089365A1

 Chemical & Physical Properties

Molecular Formula C19H28BN3O5
Molecular Weight 389.25
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