Taniborbactam
Modify Date: 2025-08-25 12:39:00
Taniborbactam structure
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Common Name | Taniborbactam | ||
|---|---|---|---|---|
| CAS Number | 1613267-49-4 | Molecular Weight | 389.25 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H28BN3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TaniborbactamTaniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1]. |
| Name | Taniborbactam |
|---|
| Description | Taniborbactam is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1]. |
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| Related Catalog | |
| Target |
IC50: <100 nM (SHV-5 β-lactamase), <100 nM (KPC-2 β-lactamase), <100 nM (VIM-2 β-lactamase), <100 nM (AmpC β-lactamase), 0.1 to 1 μM (OXA-1 β-lactamase)[1] |
| In Vitro | Taniborbactam (Example 15) is a potent inhibitor of β-lactamase, with IC50s of <100 nM for SHV-5, KPC-2, VIM-2, and AmpC β-lactamase, and 0.1 to 1 μM for OXA-1 β-lactamase, used in the research of bacterial infections[1]. |
| References |
[1]. Christopher J. Burns, et al. Beta-lactamase inhibitors. WO2014089365A1 |
| Molecular Formula | C19H28BN3O5 |
|---|---|
| Molecular Weight | 389.25 |
| InChIKey | PFZUWUXKQPRWAL-PXCJXSSVSA-N |
| SMILES | NCCNC1CCC(CC(=O)NC2Cc3cccc(C(=O)O)c3OB2O)CC1 |