2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside

Modify Date: 2024-01-11 15:52:27

2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside Structure
2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside structure
Common Name 2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside
CAS Number 1612192-00-3 Molecular Weight 354.72
Density 1.9±0.1 g/cm3 Boiling Point 556.4±60.0 °C at 760 mmHg
Molecular Formula C14H12ClFN4O4 Melting Point N/A
MSDS N/A Flash Point 290.3±32.9 °C

 Use of 2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside


2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine
Synonym More Synonyms

  Biological Activity

Description 2-Chloro-6-(furan-2-yl) purine-beta-D-(3’-deoxy-3’-fluoro)-riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 556.4±60.0 °C at 760 mmHg
Molecular Formula C14H12ClFN4O4
Molecular Weight 354.72
Flash Point 290.3±32.9 °C
Exact Mass 354.053101
LogP 1.96
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.777

 Synonyms

9H-Purine, 2-chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furanyl)-
2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine