N-[(1S,5R)-7,9-dimethyl-7,9-diazabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide dihydrochloride

Modify Date: 2025-09-25 19:42:42

N-[(1S,5R)-7,9-dimethyl-7,9-diazabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide dihydrochloride structure	Common Name	N-[(1S,5R)-7,9-dimethyl-7,9-diazabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide dihydrochloride
	CAS Number	160472-97-9	Molecular Weight	386.32
	Density	N/A	Boiling Point	574.4ºC at 760mmHg
	Molecular Formula	C₁₇H₂₅Cl₂N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	301.2ºC

Use of N-[(1S,5R)-7,9-dimethyl-7,9-diazabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide dihydrochloride

Indisetron dihydrochloride is a 5-HT3 receptor antagonist with anti-emetic activity.

Name	N-[(1S,5R)-3,9-dimethyl-3,9-diazabicyclo[3.3.1]nonan-7-yl]-1H-indazole-3-carboxamide,dihydrochloride
Synonym	More Synonyms

Description	Indisetron dihydrochloride is a 5-HT3 receptor antagonist with anti-emetic activity.
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Nakatsumi H, et al. Optimal dose period for indisetron tablets for preventing chemotherapy-induced nausea and vomiting with modified FOLFOX6: a randomized pilot study. Chemotherapy. 2012;58(6):439-44.

Boiling Point	574.4ºC at 760mmHg
Molecular Formula	C₁₇H₂₅Cl₂N₅O
Molecular Weight	386.32
Flash Point	301.2ºC
Exact Mass	385.14400
PSA	64.26000
LogP	2.94020
Vapour Pressure	3.36E-13mmHg at 25°C
InChIKey	KOYCUQMOCJHRJC-MLOZCBHJSA-N
SMILES	CN1CC2CC(NC(=O)c3n[nH]c4ccccc34)CC(C1)N2C.Cl.Cl

Indisetron hydrochloride (JAN)

Sinseron (TN)

UNII-NBN3HB12DW

N-3389

Indisetron hydrochloride

Indisetron HCl Nisshin

Sinseron

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