5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine

Modify Date: 2025-08-27 12:29:16

5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine structure	Common Name	5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine
	CAS Number	160203-74-7	Molecular Weight	270.21
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₁FN₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine

5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	[(2S,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2,5-dihydro-2-furanyl]methyl acetate
Synonym	More Synonyms

Description	5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.5±0.1 g/cm3
Molecular Formula	C₁₁H₁₁FN₂O₅
Molecular Weight	270.21
Exact Mass	270.065186
LogP	-0.79
Index of Refraction	1.566
InChIKey	KMQULMAOYWPJKG-IONNQARKSA-N
SMILES	CC(=O)OCC1C=CC(n2cc(F)c(=O)[nH]c2=O)O1

[(2S,5R)-5-(5-Fluoro-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl)-2,5-dihydro-2-furanyl]methyl acetate

2,4(1H,3H)-Pyrimidinedione, 1-[(2R,5S)-5-[(acetyloxy)methyl]-2,5-dihydro-2-furanyl]-5-fluoro-

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5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine

Use of 5’-O-Acetyl-2’,3’-dideoxy-2’,3’-didehydro-5-fluoro-uridine

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Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.