1-(4-fluorophenyl)biguanide hydrochloride

Modify Date: 2024-01-07 08:48:48

1-(4-fluorophenyl)biguanide hydrochloride Structure
1-(4-fluorophenyl)biguanide hydrochloride structure
Common Name 1-(4-fluorophenyl)biguanide hydrochloride
CAS Number 16018-83-0 Molecular Weight 231.65800
Density N/A Boiling Point 396.3ºC at 760mmHg
Molecular Formula C8H11ClFN5 Melting Point 250-254 °C(lit.)
MSDS Chinese USA Flash Point 193.5ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1-(diaminomethylidene)-2-(4-fluorophenyl)guanidine,hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 396.3ºC at 760mmHg
Melting Point 250-254 °C(lit.)
Molecular Formula C8H11ClFN5
Molecular Weight 231.65800
Flash Point 193.5ºC
Exact Mass 231.06900
PSA 97.78000
LogP 2.82110

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DU1850000
CHEMICAL NAME :
Biguanide, 1-(p-fluorophenyl)-, monohydrochloride
CAS REGISTRY NUMBER :
16018-83-0
LAST UPDATED :
199007
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H10-F-N5.Cl-H
MOLECULAR WEIGHT :
231.69
WISWESSER LINE NOTATION :
MUYZMYUM&MR DF &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
262 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,521,1967

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DU1850000

 Synonyms

1-(4-Fluorophenyl)biguanide hydrochloride
1-(diaminomethylidene)-2-(4-fluorophenyl)guanidine Hydrochloride
MFCD00051986