1-(4-fluorophenyl)biguanide hydrochloride

Names

[ Name ]:
1-(4-fluorophenyl)biguanide hydrochloride

[Synonym ]:
1-(4-Fluorophenyl)biguanide hydrochloride
1-(diaminomethylidene)-2-(4-fluorophenyl)guanidine Hydrochloride
MFCD00051986

Chemical & Physical Properties

[ Boiling Point ]:
396.3ºC at 760mmHg

[ Melting Point ]:
250-254 °C(lit.)

[ Molecular Formula ]:
C₈H₁₁ClFN₅

[ Molecular Weight ]:
231.65800

[ Flash Point ]:
193.5ºC

[ Exact Mass ]:
231.06900

[ PSA ]:
97.78000

[ LogP ]:
2.82110

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DU1850000

CHEMICAL NAME :: Biguanide, 1-(p-fluorophenyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 16018-83-0

LAST UPDATED :: 199007

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H10-F-N5.Cl-H

MOLECULAR WEIGHT :: 231.69

WISWESSER LINE NOTATION :: MUYZMYUM&MR DF &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 262 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,521,1967

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DU1850000