Bizine

Modify Date: 2024-01-02 19:38:11

Bizine Structure
Bizine structure
Common Name Bizine
CAS Number 1591932-50-1 Molecular Weight 370.317
Density N/A Boiling Point N/A
Molecular Formula C18H25Cl2N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bizine


Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects[1].

 Names

Name N-[4-(2-Hydrazinoethyl)phenyl]-4-phenylbutanamide dihydrochloride
Synonym More Synonyms

 Bizine Biological Activity

Description Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects[1].
Related Catalog
Target

Ki: 59 nM (LSD1)[1]

References

[1]. Prusevich P, et, al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. ACS Chem Biol. 2014 Jun 20;9(6):1284-93.

 Chemical & Physical Properties

Molecular Formula C18H25Cl2N3O
Molecular Weight 370.317
Exact Mass 369.137482

 Synonyms

Benzenebutanamide, N-[4-(2-hydrazinylethyl)phenyl]-, hydrochloride (1:2)
N-[4-(2-Hydrazinoethyl)phenyl]-4-phenylbutanamide dihydrochloride
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