RAS activator compound 1

Modify Date: 2024-01-22 19:48:26

RAS activator compound 1 structure	Common Name	RAS activator compound 1
	CAS Number	1579978-17-8	Molecular Weight	449.983
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₈ClN₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RAS activator compound 1

RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2.

Name	RAS activator compound 1

Description	RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK phosphorylation levels, through negative feedback on SOS1 that regulates the interaction between SOS1 and GRB2.
References	References 1. Howes JE, et al. Mol Cancer Ther. 2018 May;17(5):1051-1060. 2. Burns MC, et al. Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3401-6. View Related Products by Target Ras

Molecular Formula	C₂₅H₂₈ClN₅O
Molecular Weight	449.983

DC Chemicals Limited
China
Product Name: RAS activator compound 1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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