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1011399-77-1

1011399-77-1 structure
1011399-77-1 structure
  • Name: PPARα activator compound 3
  • Chemical Name: 6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
  • CAS Number: 1011399-77-1
  • Molecular Formula: C19H18FN3O2
  • Molecular Weight: 339.363
  • Create Date: 2020-01-12 10:02:33
  • Modify Date: 2023-01-16 13:25:35
  • PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo; reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.

Name 6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
Synonyms 6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
MFCD09473550
1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-1-(4-fluorophenyl)-3-(1-methylethyl)-
Description PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo; reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.
References References 1. Tachibana K, et al. J Biol Chem. 2018 May 15. pii: jbc.RA118.002077. View Related Products by Target PPAR
Density 1.4±0.1 g/cm3
Boiling Point 452.7±45.0 °C at 760 mmHg
Molecular Formula C19H18FN3O2
Molecular Weight 339.363
Flash Point 227.6±28.7 °C
Exact Mass 339.138306
LogP 4.98
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.684