PPARα activator compound 3

Modify Date: 2023-01-16 13:25:35

PPARα activator compound 3 Structure
PPARα activator compound 3 structure
Common Name PPARα activator compound 3
CAS Number 1011399-77-1 Molecular Weight 339.363
Density 1.4±0.1 g/cm3 Boiling Point 452.7±45.0 °C at 760 mmHg
Molecular Formula C19H18FN3O2 Melting Point N/A
MSDS N/A Flash Point 227.6±28.7 °C

 Use of PPARα activator compound 3


PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo; reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.

 Names

Name 6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
Synonym More Synonyms

 PPARα activator compound 3 Biological Activity

Description PPARα activator compound 3 is a specific PPAR activator that selectively up-regulates PPARα transcriptional activity, leading to PPARα target gene expression both in vitro and in vivo; reduces plasma triglyceride levels with similar efficiency as fenofibrate in high fructose-fed rats.
References References 1. Tachibana K, et al. J Biol Chem. 2018 May 15. pii: jbc.RA118.002077. View Related Products by Target PPAR

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 452.7±45.0 °C at 760 mmHg
Molecular Formula C19H18FN3O2
Molecular Weight 339.363
Flash Point 227.6±28.7 °C
Exact Mass 339.138306
LogP 4.98
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.684

 Synonyms

6-Cyclopropyl-1-(4-fluorophenyl)-3-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
MFCD09473550
1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-1-(4-fluorophenyl)-3-(1-methylethyl)-