P163-0892

Modify Date: 2024-07-17 18:48:44

P163-0892 Structure
P163-0892 structure
Common Name P163-0892
CAS Number 1574576-45-6 Molecular Weight 356.44
Density N/A Boiling Point N/A
Molecular Formula C19H20N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of P163-0892


P163-0892 is a potent and selective antifungal agent against Cryptococcus species. P163-0892 is predicted to show medium BBB penetration[1].

 Names

Name P163-0892

 P163-0892 Biological Activity

Description P163-0892 is a potent and selective antifungal agent against Cryptococcus species. P163-0892 is predicted to show medium BBB penetration[1].
Related Catalog
In Vitro P163-0892 (0-32 μg/mL, 48 h) shows antifungal activity with a MIC of 0.25 μg/mL and 0.5 μg/mL against Cryptococcus neoformans and Cryptococcus gattii, respectively[1]. P163-0892 has good aqueous solubility[1]. P163-0892 has no cytotoxicity and no obvious cardiotoxicity[1].
References

[1]. Li L, et al. Discovery of Novel 7-Hydroxy-5-oxo-4,5-dihydrothieno[3,2-b]pyridine-6-carboxamide Derivatives with Potent and Selective Antifungal Activity against Cryptococcus Species. J Med Chem. 2022 Aug 3.

 Chemical & Physical Properties

Molecular Formula C19H20N2O3S
Molecular Weight 356.44
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