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1574576-45-6

1574576-45-6 structure
1574576-45-6 structure
  • Name: P163-0892
  • Chemical Name: P163-0892
  • CAS Number: 1574576-45-6
  • Molecular Formula: C19H20N2O3S
  • Molecular Weight: 356.44
  • Catalog: Signaling Pathways Anti-infection Fungal
  • Create Date: 2022-09-16 12:29:38
  • Modify Date: 2024-07-17 18:48:44
  • P163-0892 is a potent and selective antifungal agent against Cryptococcus species. P163-0892 is predicted to show medium BBB penetration[1].

Name P163-0892
Description P163-0892 is a potent and selective antifungal agent against Cryptococcus species. P163-0892 is predicted to show medium BBB penetration[1].
Related Catalog
In Vitro P163-0892 (0-32 μg/mL, 48 h) shows antifungal activity with a MIC of 0.25 μg/mL and 0.5 μg/mL against Cryptococcus neoformans and Cryptococcus gattii, respectively[1]. P163-0892 has good aqueous solubility[1]. P163-0892 has no cytotoxicity and no obvious cardiotoxicity[1].
References

[1]. Li L, et al. Discovery of Novel 7-Hydroxy-5-oxo-4,5-dihydrothieno[3,2-b]pyridine-6-carboxamide Derivatives with Potent and Selective Antifungal Activity against Cryptococcus Species. J Med Chem. 2022 Aug 3.

Molecular Formula C19H20N2O3S
Molecular Weight 356.44
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