8-Hydroxyquinoline-2-Carboxylic Acid
Modify Date: 2024-01-08 12:32:26
8-Hydroxyquinoline-2-Carboxylic Acid structure
|
Common Name | 8-Hydroxyquinoline-2-Carboxylic Acid | ||
|---|---|---|---|---|
| CAS Number | 1571-30-8 | Molecular Weight | 189.167 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 426.7±30.0 °C at 760 mmHg | |
| Molecular Formula | C10H7NO3 | Melting Point | 213-214 °C | |
| MSDS | Chinese USA | Flash Point | 211.9±24.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 8-Hydroxyquinoline-2-Carboxylic AcidBAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1]. |
| Name | 8-hydroxyquinoline-2-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
| Description | BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1]. |
|---|---|
| Related Catalog | |
| Target |
IKK-α:60 nM (IC50) |
| In Vitro | BAY32-5915 (50-200 μM) has no significant inhibitory effect on NF-κB activity in melanoma cells[1]. |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 426.7±30.0 °C at 760 mmHg |
| Melting Point | 213-214 °C |
| Molecular Formula | C10H7NO3 |
| Molecular Weight | 189.167 |
| Flash Point | 211.9±24.6 °C |
| Exact Mass | 189.042587 |
| PSA | 70.42000 |
| LogP | 1.96 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.730 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | UZ9450000 |
| HS Code | 2933499090 |
| Precursor 9 | |
|---|---|
| DownStream 4 | |
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CAS#:66052-84-4| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 8-hydroxyquinoline-2-carboxylic acid |
| 8-Hydroxy-2-quinolinecarboxylic acid |
| 2-Quinolinecarboxylic acid, 8-hydroxy- |
| MFCD00168972 |
| Quinaldic acid, 8-hydroxy- |
| 8-Hydroxyquinaldic acid |