Datelliptium chloride hydrochloride
Modify Date: 2025-08-26 22:22:54
Datelliptium chloride hydrochloride structure
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Common Name | Datelliptium chloride hydrochloride | ||
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| CAS Number | 157000-76-5 | Molecular Weight | 434.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H29Cl2N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Datelliptium chloride hydrochlorideDatelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors[1][2]. |
| Name | Datelliptium chloride hydrochloride |
|---|
| Description | Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from Ellipticine (HY-15753). Datelliptium chloride hydrochloride is effective in vivo against a variety of murine solid tumors[1][2]. |
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| Related Catalog | |
| In Vitro | Datelliptium chloride hydrochloride shows cytotoxic effects after 2 hours of treatment in suspension and primary cultures of rat hepatocytes[1]. |
| In Vivo | Datelliptium chloride hydrochloride has broad antitumor activity against solid tumors of mice in vivo[2]. Datelliptium chloride hydrochloride (170 mg/kg; i.v; for 12 days) exhibits a high degree of antitumor activity at early staged disease[2]. Datelliptium chloride hydrochloride is selectively cytotoxic for solid tumors over leukemia L1210[2]. Animal Model: Mice, colon adenocarcinoma early staged disease model[2] Dosage: 170 mg/kg Administration: Intravenous injection, for 12 days Result: Highly active against colon adenocarcinoma. |
| References |
| Molecular Formula | C23H29Cl2N3O |
|---|---|
| Molecular Weight | 434.40 |
| InChIKey | QLZIAISICLKYOX-UHFFFAOYSA-N |
| SMILES | CCN(CC)CC[n+]1ccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c2c1.Cl.[Cl-] |