Aminoethyl-SS-propionic acid

Modify Date: 2024-01-09 22:03:04

Aminoethyl-SS-propionic acid Structure
Aminoethyl-SS-propionic acid structure
Common Name Aminoethyl-SS-propionic acid
CAS Number 15579-00-7 Molecular Weight 181.27600
Density 1.32g/cm3 Boiling Point 339.5ºC at 760 mmHg
Molecular Formula C5H11NO2S2 Melting Point 138-141ºC
MSDS N/A Flash Point 159.1ºC

 Use of Aminoethyl-SS-propionic acid


Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 3-(2-aminoethyldisulfanyl)propanoic acid
Synonym More Synonyms

 Aminoethyl-SS-propionic acid Biological Activity

Description Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Density 1.32g/cm3
Boiling Point 339.5ºC at 760 mmHg
Melting Point 138-141ºC
Molecular Formula C5H11NO2S2
Molecular Weight 181.27600
Flash Point 159.1ºC
Exact Mass 181.02300
PSA 113.92000
LogP 1.50150
Vapour Pressure 1.69E-05mmHg at 25°C
Index of Refraction 1.589

 Safety Information

Hazard Codes Xn

 Synonyms

MFCD07357249