Aminoethyl-SS-propionic acid

Names

[ CAS No. ]:
15579-00-7

[ Name ]:
Aminoethyl-SS-propionic acid

[Synonym ]:
MFCD07357249

Biological Activity

[Description]:

Aminoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Density]:
1.32g/cm3

[ Boiling Point ]:
339.5ºC at 760 mmHg

[ Melting Point ]:
138-141ºC

[ Molecular Formula ]:
C₅H₁₁NO₂S₂

[ Molecular Weight ]:
181.27600

[ Flash Point ]:
159.1ºC

[ Exact Mass ]:
181.02300

[ PSA ]:
113.92000

[ LogP ]:
1.50150

[ Vapour Pressure ]:
1.69E-05mmHg at 25°C

[ Index of Refraction ]:
1.589

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.