rel-Tranylcypromine

Modify Date: 2024-01-08 21:30:02

rel-Tranylcypromine structure	Common Name	rel-Tranylcypromine
	CAS Number	155-09-9	Molecular Weight	133.190
	Density	1.1±0.1 g/cm3	Boiling Point	218.3±29.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₁N	Melting Point	N/A
	MSDS	N/A	Flash Point	90.8±19.6 °C

Use of rel-Tranylcypromine

rel-Tranylcypromine (SKF 385) is a potent monoamine oxidase (MAO) inhibitor[1].

Name	tranylcypromine
Synonym	More Synonyms

Description	rel-Tranylcypromine (SKF 385) is a potent monoamine oxidase (MAO) inhibitor[1].
Related Catalog	Research Areas >> Cardiovascular Disease Research Areas >> Endocrinology Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
In Vivo	rel-Tranylcypromine (SKF 385) (0.1 to 3.0 mg/kg; intravenous injection; mongrel dogs, weighing 5-10 kg) elevates the blood pressure. The extent and duration of the rise of blood pressure by the drug depended on the dose administered. When the administration of rel-Tranylcypromine is repeated again and again, the depressor response of the animal to rel-Tranylcypromine is usually obtained[1].
References	[1]. TODA N, et al. The sympathomimetic effects of SKF-385 on blood pressure in dog. Jpn J Pharmacol. 1962;12:166-179.

Density	1.1±0.1 g/cm3
Boiling Point	218.3±29.0 °C at 760 mmHg
Molecular Formula	C₉H₁₁N
Molecular Weight	133.190
Flash Point	90.8±19.6 °C
Exact Mass	133.089142
PSA	26.02000
LogP	1.25
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.584

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GZ2450100

CHEMICAL NAME :: Cyclopropylamine, 2-phenyl-, trans-(+-)-

CAS REGISTRY NUMBER :: 155-09-9

BEILSTEIN REFERENCE NO. :: 3195803

LAST UPDATED :: 199803

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H11-N

MOLECULAR WEIGHT :: 133.21

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 5714 ug/kg

TOXIC EFFECTS :: Cardiac - arrhythmias (including changes in conduction)

REFERENCE :: JATOD3 Journal of Analytical Toxicology. (Preston Pub. Inc., POB 48312, Niles, IL 60648) V.1- 1977- Volume(issue)/page/year: 20,301,1996

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 64 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 166,449,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - excitement

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,1727,1971

HS Code	2921499090

Precursor 0
DownStream 3
CAS#:14371-10-9 Cinnamic aldehyde CAS#:23580-89-4 methyl(3-phenyl... CAS#:103531-48-2 6-fluoro-7-(1-p...

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

(1R,2S)-2-Phenylcyclopropanamine

2-Phenyl-1-aminocyclopropane, trans-

Tranylcypromine

Tranylcypromine (base and/or unspecified salts)

EINECS 205-841-9

(-)-Tranylcypromine

(1R,2S)-2-phenylcyclopropan-1-amine

Parnitene

SKF Trans-385

(1R)-2-Phenylcyclopropanamine

Cyclopropanamine,2-phenyl-,(1R,2S)-rel

Cyclopropanamine, 2-phenyl-, trans-

Tylciprine

dl-Tranylcypromine

Cyclopropanamine, 2-phenyl-, (1R,2S)-

Parnate

UNII:3E3V44J4Z9

Cyclopropanamine, 2-phenyl-, (1R)-

Cyclopropanamine, 2-phenyl-, (1R-trans)- (9CI)

(-)-2-phenylcyclopropyl-1-amine

DC Chemicals Limited
China
Product Name: rel-Tranylcypromine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cyclopropanamine,2-phenyl-, (1R,2S)-rel-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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