LY 222306

Modify Date: 2025-08-26 19:34:34

LY 222306 structure	Common Name	LY 222306
	CAS Number	154446-98-7	Molecular Weight	433.42
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₃N₅O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LY 222306

LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

Name	LY 222306

Description	LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer
Target	Ki: 0.77 nM (GARFT)[1]
References	[1]. Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.

Molecular Formula	C₁₉H₂₃N₅O₇
Molecular Weight	433.42
InChIKey	FNQHSRGPACXGKI-UHFFFAOYSA-N
SMILES	NC1=NC2=NCC(CCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)o3)CC2C(=O)N1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LY 222306
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
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