LY 222306

Modify Date: 2024-01-12 21:16:31

LY 222306 Structure
LY 222306 structure
Common Name LY 222306
CAS Number 154446-98-7 Molecular Weight 433.42
Density N/A Boiling Point N/A
Molecular Formula C19H23N5O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY 222306


LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

 Names

Name LY 222306

 LY 222306 Biological Activity

Description LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
Related Catalog
Target

Ki: 0.77 nM (GARFT)[1]

References

[1]. Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.

 Chemical & Physical Properties

Molecular Formula C19H23N5O7
Molecular Weight 433.42
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