NCT-502

Modify Date: 2023-01-11 12:13:13

NCT-502 structure	Common Name	NCT-502
	CAS Number	1542213-00-2	Molecular Weight	395.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₀F₃N₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NCT-502

NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH[1].

Name	NCT-502

Description	NCT-502 is a human phosphoglycerate dehydrogenase (PHGDH) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC50 of 3.7 μM against PHGDH[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 3.7 μM (PHGDH)[1]
In Vitro	NCT-502 is cytotoxic to MDA-MB-468, with an EC50 of 15.2 µM[1].
References	[1]. Rohde JM, et al. Discovery and optimization of piperazine-1-thiourea-based human phosphoglycerate dehydrogenase inhibitors. Bioorg Med Chem. 2018 May 1;26(8):1727-1739.

Molecular Formula	C₁₈H₂₀F₃N₅S
Molecular Weight	395.45
Storage condition	2-8℃

DC Chemicals Limited
China
Product Name: NCT-502
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Get all suppliers and price by the below link:

NCT-502 suppliers

NCT-502 price

NCT-502

Use of NCT-502

Names

NCT-502 Biological Activity

Chemical & Physical Properties