Simetride

Modify Date: 2024-01-10 01:53:10

Simetride Structure
Simetride structure
Common Name Simetride
CAS Number 154-82-5 Molecular Weight 498.61100
Density 1.147g/cm3 Boiling Point 682.6ºC at 760 mmHg
Molecular Formula C28H38N2O6 Melting Point N/A
MSDS N/A Flash Point 366.6ºC

 Use of Simetride


Simetride is an analgesic agent. Simeicui is used for pain relief[1].

 Names

Name 2-(2-methoxy-4-propylphenoxy)-1-[4-[2-(2-methoxy-4-propylphenoxy)acetyl]piperazin-1-yl]ethanone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.147g/cm3
Boiling Point 682.6ºC at 760 mmHg
Molecular Formula C28H38N2O6
Molecular Weight 498.61100
Flash Point 366.6ºC
Exact Mass 498.27300
PSA 77.54000
LogP 3.61320
Vapour Pressure 1.73E-18mmHg at 25°C
Index of Refraction 1.548
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TK9700000
CHEMICAL NAME :
Piperazine, 1,4-bis((2-methoxy-4-propylphenoxy)acetyl)-
CAS REGISTRY NUMBER :
154-82-5
BEILSTEIN REFERENCE NO. :
0772468
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C28-H38-N2-O6
MOLECULAR WEIGHT :
498.68
WISWESSER LINE NOTATION :
T6N DNTJ AV1OR D3 BO1& DV1OR D3 BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1025 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,206,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 85,715,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1968 Volume(issue)/page/year: -,84,1968

 Safety Information

HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Piperazine,1,4-bis((2-methoxy-4-propylphenoxy)acetyl)
Simetridum [INN-Latin]
1,4-Bis-(2-methoxy-4-propyl-phenoxyacetyl)-piperazin
Kyorin AP 2
Simetride
Simetrida [INN-Spanish]
1,4-Bis((2-methoxy-4-propylphenoxy)acetyl)piperazine
Simetridum
AP 2
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