Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Simetride
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

154-82-5

154-82-5 structure

154-82-5 structure

Name: Simetride
Chemical Name: 2-(2-methoxy-4-propylphenoxy)-1-[4-[2-(2-methoxy-4-propylphenoxy)acetyl]piperazin-1-yl]ethanone
CAS Number: 154-82-5
Molecular Formula: C₂₈H₃₈N₂O₆
Molecular Weight: 498.61100
Catalog: Research Areas Neurological Disease
Create Date: 2018-09-20 12:51:42
Modify Date: 2025-08-25 11:45:54
Simetride is an analgesic agent. Simeicui is used for pain relief[1].

Name	2-(2-methoxy-4-propylphenoxy)-1-[4-[2-(2-methoxy-4-propylphenoxy)acetyl]piperazin-1-yl]ethanone
Synonyms	Piperazine,1,4-bis((2-methoxy-4-propylphenoxy)acetyl) Simetridum [INN-Latin] 1,4-Bis-(2-methoxy-4-propyl-phenoxyacetyl)-piperazin Kyorin AP 2 Simetride Simetrida [INN-Spanish] 1,4-Bis((2-methoxy-4-propylphenoxy)acetyl)piperazine Simetridum AP 2

Description	Simetride is an analgesic agent. Simeicui is used for pain relief[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Mlyczyńska E, et, al. Anti-Apoptotic Effect of Apelin in Human Placenta: Studies on BeWo Cells and Villous Explants from Third-Trimester Human Pregnancy. Int J Mol Sci. 2021 Mar 9;22(5):2760.

Density	1.147g/cm3
Boiling Point	682.6ºC at 760 mmHg
Molecular Formula	C₂₈H₃₈N₂O₆
Molecular Weight	498.61100
Flash Point	366.6ºC
Exact Mass	498.27300
PSA	77.54000
LogP	3.61320
Vapour Pressure	1.73E-18mmHg at 25°C
Index of Refraction	1.548
Storage condition	-20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TK9700000

CHEMICAL NAME :: Piperazine, 1,4-bis((2-methoxy-4-propylphenoxy)acetyl)-

CAS REGISTRY NUMBER :: 154-82-5

BEILSTEIN REFERENCE NO. :: 0772468

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C28-H38-N2-O6

MOLECULAR WEIGHT :: 498.68

WISWESSER LINE NOTATION :: T6N DNTJ AV1OR D3 BO1& DV1OR D3 BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1025 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,206,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 85,715,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1968 Volume(issue)/page/year: -,84,1968

HS Code	2933599090

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.