KSPWFTTL

Modify Date: 2025-08-25 12:27:15

KSPWFTTL Structure
KSPWFTTL structure
Common Name KSPWFTTL
CAS Number 153049-05-9 Molecular Weight 979.13
Density N/A Boiling Point N/A
Molecular Formula C48H70N10O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KSPWFTTL


KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].

 Names

Name KSPWFTTL

 KSPWFTTL Biological Activity

Description KSPWFTTL is an immunodominant Kb-restricted epitope from the p15E transmembrane protein. KSPWFTTL can restore susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes[1][2].
Related Catalog
In Vitro KSPWFTTL is derived from the retroviral p15 TM envelope protein. The cytolytic T-lymphocyte (CTL)-insusceptible, variant cl.18-5 clonal line, after pulsed with the KSPWFTTL peptide, becomes susceptible to lysis by antiviral CTL[2].
References

[1]. White HD, et, al. An immunodominant Kb-restricted peptide from the p15E transmembrane protein of endogenous ecotropic murine leukemia virus (MuLV) AKR623 that restores susceptibility of a tumor line to anti-AKR/Gross MuLV cytotoxic T lymphocytes. J Virol. 1994 Feb;68(2):897-904.

[2]. Rich RF, et, al. Antiretroviral cytolytic T-lymphocyte nonresponsiveness: FasL/Fas-mediated inhibition of CD4(+) and CD8(+) antiviral T cells by viral antigen-positive veto cells. J Virol. 1999 May;73(5):3826-34.

 Chemical & Physical Properties

Molecular Formula C48H70N10O12
Molecular Weight 979.13
InChIKey ACAFPRSTSWTCSS-ALQLYSEESA-N
SMILES CC(C)CC(NC(=O)C(NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C1CCCN1C(=O)C(CO)NC(=O)C(N)CCCCN)C(C)O)C(C)O)C(=O)O
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