AB-MECA
Modify Date: 2024-01-23 16:55:48
AB-MECA structure
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Common Name | AB-MECA | ||
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| CAS Number | 152918-26-8 | Molecular Weight | 399.40400 | |
| Density | 1.68g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H21N7O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of AB-MECAAB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors. |
| Name | (2S,3S,4R,5R)-5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide |
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| Synonym | More Synonyms |
| Description | AB-MECA is a high affinity A3 adenosine receptor agonist, has high affinity for recombinant A1 and A3 receptors. |
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| Related Catalog | |
| References |
| Density | 1.68g/cm3 |
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| Molecular Formula | C18H21N7O4 |
| Molecular Weight | 399.40400 |
| Exact Mass | 399.16600 |
| PSA | 163.93000 |
| LogP | 0.88030 |
| Index of Refraction | 1.789 |
| Storage condition | 2-8℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor.
Mol. Pharmacol. 45 , 978-982, (1994) The rat A3 adenosine receptor (AR) is a recently characterized AR subtype cloned from testis and brain cDNA libraries. N6-2-(4-Amino-3-[125I]iodophenyl)ethyladenosine, a high affinity A1AR agonist, ha... |
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A role for central A3-adenosine receptors. Mediation of behavioral depressant effects.
FEBS Lett. 336 , 57-60, (1993) The behavioral effects of a selective A3 adenosine receptor agonist 3-IB-MECA (N6-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine) in mice and the localization of radioligand binding sites in mouse bra... |
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Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.
J. Med. Chem. 37 , 636-646, (1994) Adenosine analogues modified at the 5'-position as uronamides and/or as N6-benzyl derivatives were synthesized. These derivatives were examined for affinity in radioligand binding assays at the newly ... |
| N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine |
| [3H]AB-MECA |
| AB-MECA |